Colorectal Group

Recent Publications

Burke JP, Cunningham MF, Sweeney C, Docherty NG, O’Connell PR. N-cadherin is overexpressed in Crohn’s stricture fibroblasts and promotes intestinal fibroblast migration. Inflamm Bowel Dis 2011 Aug;17(8):1665-73. PMID 21287659.

Doherty GA, Miksad RA, Cheifetz AS, Moss AC. Comparative cost-effectiveness of strategies to prevent postoperative clinical recurrence of Crohn's disease. Inflamm Bowel Dis. 2011 Sep 8. doi: 10.1002/ibd.21904. [Epub ahead of print] PMID: 21905173[PubMed - as supplied by publisher]

Doherty GA, Moss AC, Cheifetz AS. Capsule endoscopy for small-bowel evaluation in Crohn's disease. Gastrointest Endosc. 2011 Jul;74(1):167-75. Epub 2011 Apr 17. Review. No abstract available. PMID:21497806 [PubMed - indexed for MEDLINE]

Doran D, Burke JP, Hanly AM, Winter DC. Prophylactic colectomy for hyperplastic polyposis. Ir J Med Sci. 2011 Mar;180(1):269-70. Epub 2009 Sep 26. PMID: 19784713 [PubMed - indexed for MEDLINE]

Eogan M, O’Brien C, Daly L, Behan M, O’Connell PR, O’Herlify C. The dual influences of age and obstertric history on fecal continence in parous women. Int J. Gynaecol Obstet 2011 Feb;112(2):93-7.PMID 21078512

Heetun Z, Doherty GA. Restoring the regulatory regime in IBD: Do anti-TNF agents rescue treg? Inflamm Bowel Dis. 2011 Oct 21. PMID: 22021154

Heeney A, Mulsow J, Hyland JM. Treatment and outcomes of anorectal melanoma. Surgeon 2011 Feb;9(1):27-32. PMID 21195328

Joyce EA, Kavanagh DO, O’Connell PR, Hyland JM. Massive intra-abdominal haemorrhage following stapled haemorrhoidopexy. Int. J. Colorectal Dis 2011 Jul 6. PMID 21732078

Kevans D, Wang LM, Sheahan K, Hyland J, O’Donoghue D, Mulcahy H, O’Sullivan J. Epithelial-Mesenchymal Transition (EMT) Protein Expression in a Cohort of Stage II Colorectal Cancer Patients with characterised Tumor Budding and Mismatch Repair Protein Status. Int. J. Surg. Pathol 2011 Jul 26. PMID 21791486

Kevans D, Gorman S, Toestto M, Sheahan K, O’Donoghue D, Mulcahy H, O’Sullivan J. Clusterin and Chemotherapy Sensitivity under Normoxic and Graded Hypoxic Conditions in Colorectal Cancer. J. Gastrointest Cancer 2011 Apr 13. PMID 21487682

Kennedy RD, Bylesjo M, Kerr P, Davison T, Black JM, Kay EW, Holt RJ, Proutski V, Ahdesmaki M, Farztdinov V, Goffard N, Hey P, McDyer F, Mulligan K, Mussen J, O'Brien E, Oliver G, Walker SM, Mulligan JM, Wilson C, Winter A, O'Donoghue D, Mulcahy H,

Kennedy RD, Byesjo M, Kerr P, Winter A, O’Donoghue D, Mulcahy H, O’Sullivan J, Sheahan K, Hyland J et al. Development and independent validation of a prognostic assay for stage II colon cancer using formalin-fixed paraffin-embedded tissue. J. Clin Oncol 2011 Dec 10;29(35):4620-6. PMID 22067406

Kennelly RP, Heeney A, White A, Fennelly D. Sheahan K. Hyland JM. O’Connell PR. Winter DC. A prospective analysis of patient outcome following treatment of T3 rectal cancer with neo-adjuvant chemoradiotherapy and transanal excision. Int. J. Colorectal Dis. 2011 Dec 17. PMID 22173716

Leyden JE, Doherty GA, Hanley A, McNamara DA, Shields C, Leader M, Murray FE, Patchett SE, Harewood GC. Quality of colonoscopy performance among gastroenterology and surgical trainees: a need for common training standards for all trainees? Endoscopy. 2011 Nov;43(11):935-40. Epub 2011 Oct 13. PMID: 21997723 [PubMed - in process]

Maguire A, Sheahan K. Pathology of oesophagitis. Histopathology 2011 Aug 22. PMID 21864316

Martin ST, Heeney A, Pierce C, O’Connell PR, Hyland JM, Winter DC. Use of an electrothermal bipolar sealing device in ligation of major mesenteric vessels during laparoscopic colorectal resection. Tech Coloproctol 2011 Jul 15. PMID 21761166

Medani M, Collins D, Docherty NG, Baird AW, O’Connell PR, Winter DC. Emerging role of hydrogen sulphide in colonic physiology and pathophysiology. Inflamm Bowel Dis. 2011 Jul;17(7):1620-5. PMID 21674719

Michielsen AJ, Hogan AE, Marry J, Tosetto M, Cox F. Hyland JM, Sheahan KD, O’Donoghue DP, Mulcahy HE, Ryan EJ, O’Sullivan JN. Tumour tissue microenvironment can inhibit dendritic cell maturation in colorectal cancer. PLoS One 2011;6(11):e27944. PMID 22125641

Mulsow J. Winter DC. Sphincter preservation for distal rectal cancer – a goal worth achieving at all costs? World J Gastroenterol 2011 Feb21;17(7):855-61. PMID 21412495

Martin ST, Tevlin R, Heeney A Peirce C, Hyland JM, Winter DC. How I do it: the stapled ileal j pouch at restorative proctocolectomy. Tech Coloproctol 2011 Dec; 15(4):451-4. PMID21984050

McDermott E, Keegan D, Hall B, Mhuruchu EN, Murphy S, Doherty G, O'Donoghue D, Mulcahy H. Mycophenolate mofetil following intolerance or failure of thiopurine therapy in inflammatory bowel diseases. Aliment Pharmacol Ther. 2011 Oct;34(8):1040-2. PMID:21933214

O'Sullivan J, Sheahan K, Hyland J, Dhir R, Bathe OF, Winqvist O, Manne U, Shanmugam C, Ramaswamy S, Leon EJ, Smith WI Jr, McDermott U, Wilson RH, Longley D, Marshall J, Cummins R, Sargent DJ, Johnston PG, Harkin DP. Development and independent validation of a prognostic assay for stage II colon cancer using formalin-fixed paraffin-embedded tissue. J Clin Oncol. 2011 Dec 10;29(35):4620-6. Epub 2011 Nov 7.PMID:22067406[PubMed - in process]

Peirce C. Martin ST, Hyland JM. The use of minimally invasive surgery in the management of idiopathic omental torsion: The diagnostic and therapeutic role of laaroscopy. Int. J. Surg. Case Rep. 2011;2(6):125-7. PMID 22096703

Peirce C, O’Herlihy C, O’Connell PR, Jones JF. Effect of injury on S1 dorsal root ganglis in an experimental model of neurolpathic faecal incontinence. Br J. Surg 2011 Aug;98(8):1155-9 PMID 21618494

Rogers AC, Hanly AM, Collins D, Baird AW, Winter DC. Loss of the Calcium-Sensing Receptor in Colonic Epithelium is a Key Event in the Pathogenesis of Colon Cancer. Clin Colorectal Cancer 2011 Jun 30. PMID 21723793

Rowan F, Coffey JC, O’Connell PR, Docherty NG, Murphy M, Murphy TB. Ileal Pouch Microbial Diversity. Ann Surg 2011 Sep 1. PMID 21892071.

Slattery E, Keegan D, Hyland J, O’Donoghue D, Mulcahy HE. Surgery, Crohn’s disease, and the biological era: has there been an impact? J. Clin Gastroenterol 2011 Sep:45(8):691-3. PMID 21135702.

Slattery E, Keegan D. Hyland J. Mulcahy H. O’Donoghue D. Surgical rates in ulcerative colitis: have we made a difference? Scand J. Gastroenterol 2011 Jan;46(1):122-3. PMID 20809770.

Vaughn BP, Doherty GA, Gautam S, Moss AC, Cheifetz AS Screening for tuberculosis and hepatitis B prior to the initiation of anti-tumor necrosis therapy..Inflamm Bowel Dis. 2011 Sep 26. doi: 10.1002/ibd.21824. [Epub ahead of print]PMID:21953829[PubMed - as supplied by publisher]

Winter DC, Just as the twig is bent, the tree’s inclined: lessons from the future of surgical education. Arch Surg 2011 Jul;146(7):835. PMID 21894622


Collins D, Hogan AM, Winter DC. Microbial and viral pathogens in colorectal cancer. Lancet Oncol 2011 May;12(5):504-12. PMID 21067973

Collins D, Kopic S. Bachlechner J, Ritter M, Winter DC, Geibel JP. Hypoxia Inhibits Colonic Ion Transport via Activation of AMP Kinase. Ann Surg 2011 May 10. PMID 21562404