Rheumatology Group

Recent Publications

Adams R, Craig BM, Walsh CD, Veale Dj, Bresnihan B, Fitzgerald O, Barry M. The impact of a revised EQ-5D population scoring on preference-based utility scores in an inflammatory arthritis cohort. Value Health 2011 Sept-Oct;14(6):921-7. PMID 21914514

Biniecka M, Fox E, Gao W, Ng CT, Veale DJ, Fearon U, O’Sullivan J. Hypoxia incudes mitochondrial mutagenesis and dysfunction in inflammatory arthritis. Arthritis Rheum 2011 April 11. PMID 21484771

Biniecka M, Kennedy A, Ng CT, Chang TC, Balogh E, Fox E, Veale DJ, Fearon U, O’Sullivan JN. Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis. Arthritis Res Ther 2011 Jul 25;13(4):R121. PMID 21787418.

Connolly M, Veale DJ, Fearon U. Actue serum amyloid A regulates cytoskeletal rearrangement, cell matrix interactions and promotes cell migration in rheumatoid arthritis. Ann Rheum Dis. 2011 Jul;70(7):1296-303. PMID 21482536

Connolly M, Mullan RH, McCormick J, Matthews C, Sullivan O, Kennedy A, Fitzgerald O, Poole AR, Bresnihan B, Veale DJ, Fearon U. A-SAA regulates TNFα and matrix turnover and predicts disease progression in patients pre/post biologic therapy. Arthritis Rheum 2011 Nov 10. PMID 22076945

de Hair MJ, Harty LC, Gerlag DM, Pitzalis C, Veale DJ, Tak PP. Synovial tissue
analysis for the discovery of diagnostic and prognostic biomarkers in patients
with early arthritis. J Rheumatol. 2011 Sep;38(9):2068-72. PMID: 21885519

Fearon U. Interleukin-27: A Master Regulator in Inflammation. Arthritis Rheum 2011 Aug;63(8):2157-60. PMID 21384331

Fransen J, Johnson SR, van den Hoogen F, Baron M, Allanore Y, Carreira PE,
Czirják L, Denton CP, Distler O, Furst DE, Gabrielli A, Herrick A, Inanc M,
Kahaleh B, Kowal-Bielecka O, Medsger TA Jr, Mueller-Ladner U, Riemekasten G,
Sierakowski S, Valentini G, Veale D, Vonk MC, Walker U, Chung L, Clements PJ,
Collier DH, Csuka ME, Jimenez S, Merkel PA, Seibold JR, Silver R, Steen V,
Tyndall A, Matucci-Cerinic M, Pope JE, Khanna D. Items for developing revised
classification criteria in systemic sclerosis: Results of a consensus exercise
with the ACR/EULAR working committee for classification criteria in systemic
sclerosis. Arthritis Care Res (Hoboken). 2011 Nov 3. doi: 10.1002/acr.20679. PMID: 22052558.

Harty LC, Biniecka M, O'Sullivan J, Fox E, Mulhall K, Veale DJ, Fearon U.
Mitochondrial mutagenesis correlates with the local inflammatory environment in
arthritis. Ann Rheum Dis. 2011 Dec 2. PMID 22121133

Huang A, Harty LC, Ryan CM, Veale DJ. Clinical images: Infliximab therapy of polyarticular small joint sarcoid arthritis. Arthritis Rheum 2011 Jul;63(7):2030. PMID 21425127

Kennedy A, NgCT, Chang TC, Biniecka M, O’Sullivan JN, Heffernan E, Fearon U, Veale DJ. TNF blocking therapy alters joint inflammation and hypoxia. Arthritis Rheum 2011.Vol 63, No. 4 April 2011 pp923-932. PMID 21225682

Moran EM, Connolly M, Gao W, McCormick J, Fearon U, Veale DJ. IL-17A induction of angiogenesis, cell migration and cytoskeletal rearrangement. Arthritis Rheum 2011 Nov;63(11):3263-73. PMID 21834066

Moran EM, Heydrich R, Ng CT, Sabet TP, McCormick J. Sieper J, Appel H, Fearon U, Veale DJ. IL-17A expression is localised to both mononuclear and polymorphonuclear synovial cell infiltrates. PLoS One 2011;6(8):e24048. PMID 21887369

Nic An Ultaigh S, Saber TP, McCormick J, Connolly M, Dellacasagrande J, Keogh B, McCormack W, Reilly M, O’Neill L, McGuirk P, Fearon U, Veale DJ. Blockage of Toll-like receptor 2 prevents spontaneous cytokine release from theumatoid arthritis ex vivo synovial explants cultures. Arthritis Res & Ther 2011  Feb 23;13(1):R33. PMID 21345222

Pontifex EK, Gerlag DM, Gogarty M, Vinkenoog M, Gibbs A, Burgman I, Fearon U, Bresnihan B, Tak PP, Gibney RG, Veale DJ, FitzGerald O. Change in CD3 positive T-cell expression in psoriatic arthritis synovium correlates with changes in DAS28 and magnetic resonance imaging synovitis scores following initiation of biologic therapy – a single centre, open-label study. Arthritis Res Ther 2011 Jan 27;13(1):R7. PMID 21272347

Reid A, Brady A, Blake C, Mongey AB, Veale DJ, Fitzgerald O, Cusack T. Randomised controlled trial examining the effect of exercise in people with rheumatoid arthritis taking anti-TNFα therapy medication. BMC Musculoskelet Disord. 2011 Jan 13;12:11. PMID 21232112

Saber T, Veale DJ, Balogh E, McCormick J. Nic an Ultaigh S, Connolly M, Fearon U. Toll-Like Receptor 2 Induced Angiogenesis and Invasion is Mediated through the Tie2 Signalling Pathway in Rheumatoid Arthritis. PLoS One 2011;6(8):e23540. PMID 21858161.

van de Sande MG Gerlag DM,  Lodd BM, van Baarsen LG, Alivernini S, Codullo V,  Felea I,Vieira-Sousa E, Fearon U, Reece R, Montecucco C, Veale DJ, Pitzalis C, Emery P, Klareskog L, McInnes IB, Tak PP.  Evaluating Antirheumatic Treatment Using Synovial Biopsy: a Guideline for Standardisation to Be Used in Clinical Trial. Ann Rheum Dis, 2011 Mar;70(3):423-7. PMID 21109518

Veale DJ New Therapies and New Goals for Psoriatic Arthritis.  Arthritis & Rheum 2011 Apr;63(4):874-6. PMID 21128255.

Walsh CE, Ryan EJ, O'Farrelly C, Golden-Mason L, Fitzgerald O, Veale DJ,
Bresnihan B, Fearon U. Differential Expression of NK Receptors CD94 and NKG2A by T Cells in Rheumatoid Arthritis Patients in Remission Compared to Active Disease. PLoS One. 2011;6(11):e27182 PMID: 22102879; PubMed Central PMCID: PMC3216944.