Clinical Research

There is an active research programs within the Department of Critical Care Medicine in SVUH.

Prof Alistair Nichol, Critical Care Medicine

Clinical research activity includes collaboration with the Australian and New Zealand Intensive Care Research Centre (ANZIC), an internationally renowned research institute lead by Prof Jamie Cooper and Prof Rinaldo Bellomo. We are also involved with the ESICM Trials Group.

St Vincentís University Hospital Intensive Care Unit is currently enrolling patients for a number of clinical research studies;.

HARP 2

(Hydroxymethylglutaryl-CoA Reductase Inhibition with Simvastatin in Acute Lung Injury to Reduce Pulmonary Dysfunction) . A phase II randomised controlled trial of simvastatin in patient with Acute Lung Injury. Lead Prof Danny Mac Auley (Belfast).

ARISE

Australasian Resuscitation In Sepsis Evaluation Randomised Controlled Trial. A Multi-centre, randomised controlled trial of early goal-directed therapy in patients presenting to the Emergency Department with severe sepsis. Lead Prof Sany Peake (SA, Australia). http://www.anzicrc.monash.org/arise-rct.html

TRANSFUSE

STandaRd Issue TrANsfusion versuS Fresher red blood cell Use in intenSive care (TRANSFUSE) – a randomized controlled trial. Lead Prof Jamie Cooper (Vic, Australia). http://www.anzicrc.monash.org/transfuse-rct.html

PHARLAP

A multi-centre randomised controlled trial of an Open Lung Strategy including Permissive Hypercapnia, Alveolar Recruitment and Low Airway Pressure in patients with acute respiratory distress syndrome. A Multi-centre, phase II randomised controlled trial of an open lung ventilation strategy in patients with acute respiratory distress syndrome. Lead Prof A Nichol (Dublin). http://www.anzicrc.monash.org/pharlaprct.html

AKI

Prospective Validation of Acute Kidney Injury Biomarkers and Definitions in Critically ill Patients. This observational study is led by Prof P Murray (Dublin).

IC-GLOSSARI

The Intensive Care GLObal Study on Severe Acute Respiratory Infection

Lung – safe

The Intensive Care GLObal Study on Severe Acute Respiratory Infection We have agreed to join the European CLIN-Net hospital network to participate in the Hospital- and Laboratory Networks CLIN-Net and LAB-Net supporting the consortia COMBACTE, Academic Partners of COMBACTE (APC) Consortium for surveillance, prevention and treatment of hospital-acquired S. aureus infections, and Academic Partners of COMBACTE 2 (APC2).

http://www.esicm.org/research/lung-safe

http://www.esicm.org/research/icglossari

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