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Treatment of invasively ventilated adults with Early Activity and Mobilisation – TEAM Trial

The sickest patients in intensive care units (ICU) receive prolonged, invasive support for their breathing. This is commonly managed with no active exercise out of bed, and results in severe muscle weakness, longer hospital stay and poor recovery. We have found that early activity and mobilisation during invasive breathing support is safe and may improve survival and recovery. We will test whether early activity and mobilisation is really better.

Key Eligibility Criteria

– Aged 18 years or older
– Intubated and has received mechanical ventilation for ≥ 24 hours
– Expected to remain intubated and invasively mechanically ventilatied the day after

Therapeutic Area
Intensive Care Unit (ICU)
Type of Study
Phase III multi-centre randomised controlled trial.
Study Status
Open Recruiting
Monash University, Melbourne, Austrialia
Principal Investigator
Professor Alistair Nichol